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Publications

These publications are solely or partly based on data collected in the SITS International registry

112. Halúsková S, Herzig R, Mikulík R, Bělašková S, Reiser M, Jurák L, Václavík D, Bar M, Klečka L, Řepík T, Šigut V, Tomek A, Hlinovský D, Šaňák D, Vyšata O, Vališ M, On Behalf Of The Czech Sits Investigators. Intravenous Thrombolysis in Posterior versus Anterior Circulation Stroke: Clinical Outcome Differs Only in Patients with Large Vessel Occlusion. Biomedicines. 2024 Feb 9;12(2):404. doi: 10.3390/biomedicines12020404. PMID: 38398006; PMCID: PMC10887309. [PubMed]

111. Cappellari M, Pracucci G, Saia V, Fainardi E, Casetta I, Sallustio F, Ruggiero M, Longoni M, Simonetti L, Zini A, Lazzarotti GA, Giannini N, Da Ros V, Diomedi M, Vallone S, Bigliardi G, Limbucci N, Nencini P, Ajello D, Marcheselli S, Burdi N, Boero G, Bracco S, Tassi R, Boghi A, Naldi A, Biraschi F, Nicolini E, Castellan L, Del Sette M, Allegretti L, Sugo A, Buonomo O, Dell’Aera C, Saletti A, De Vito A, Lafe E, Mazzacane F, Bergui M, Cerrato P, Feraco P, Piffer S, Augelli R, Vit F, Gasparotti R, Magoni M, Comelli S, Melis M, Menozzi R, Scoditti U, Cavasin N, Critelli A, Causin F, Baracchini C, Guzzardi G, Tarletti R, Filauri P, Orlandi B, Giorgianni A, Cariddi LP, Piano M, Motto C, Gallesio I, Sepe FN, Romano G, Grasso MF, Pauciulo A, Rizzo A, Comai A, Franchini E, Sicurella L, Galvano G, Mannino M, Mangiafico S, Toni D, On Behalf Of The Iretas Group. IV thrombolysis plus thrombectomy versus IV thrombolysis alone for minor stroke with anterior circulation large vessel occlusion from the IRETAS and Italian SITS-ISTR cohorts. Neurol Sci. 2023 Dec;44(12):4401-4410. doi: 10.1007/s10072-023-06948-w. Epub 2023 Jul 17. PMID: 37458843. [PubMed]

110. Klail T, Sedova P, Vinklarek JF, Kovacova I, Bar M, Cihlar F, Cernik D, Kočí L, Jura R, Herzig R, Husty J, Kocher M, Kovar M, Nevšímalová M, Raupach J, Rocek M, Sanak D, Sevcik P, Skoloudik D, Sramek M, Vanicek J, Vaško P, Vaclavik D, Tomek A, Mikulik R. Safety and Efficacy of Baseline Antiplatelet Treatment in Patients Undergoing Mechanical Thrombectomy for Ischemic Stroke: Antiplatelets Before Mechanical Thrombectomy. J Vasc Interv Radiol. 2023 Sep;34(9):1502-1510.e12. doi: 10.1016/j.jvir.2023.05.017. Epub 2023 May 14. PMID: 37192724. [PubMed]

109. Cappellari M, Saia V, Pracucci G, Casetta I, Fainardi E, Sallustio F, Ruggiero M, Romoli M, Simonetti L, Zini A, Lazzarotti GA, Orlandi G, Vallone S, Bigliardi G, Renieri L, Nencini P, Semeraro V, Boero G, Bracco S, Tassi R, Castellano D, Naldi A, Biraschi F, Nicolini E, Del Sette B, Malfatto L, Allegretti L, Tassinari T, Tessitore A, Ferraù L, Saletti A, De Vito A, Lafe E, Cavallini A, Bergui M, Bosco G, Feraco P, Bignamini V, Mandruzzato N, Vit F, Mardighian D, Magoni M, Comelli S, Melis M, Menozzi R, Scoditti U, Cester G, Viario F, Stecco A, Fleetwood T, Filauri P, Sacco S, Giorgianni A, Cariddi LP, Piano M, Motto C, Gallesio I, Sepe F, Romano G, Grasso MF, Lozupone E, Fasano A, Comai A, Franchini E, Bruni S, Silvestrini M, Chiumarulo L, Petruzzelli M, Pavia M, Invernizzi P, Puglielli E, Casalena A, Pedicelli A, Frisullo G, Amistà P, Russo M, Allegritti M, Caproni S, Mangiafico S, Toni D; IRETAS Group. Stroke with large vessel occlusion in the posterior circulation: IV thrombolysis plus thrombectomy versus IV thrombolysis alone. J Thromb Thrombolysis. 2023 Oct;56(3):454-462. doi: 10.1007/s11239-023-02844-4. Epub 2023 Jun 28. PMID: 37378700. [PubMed]

108. Tsivgoulis G, Palaiodimou L, Stefanou MI, Theodorou A, Kõrv J, Nunes AP, Candelaresi P, Dall’Ora E, Sariaslani P, Provinciali L, Conforto AB, Cidrao AAL, Karapanayiotides T, Ahmed N. Predictors of functional outcome after symptomatic intracranial hemorrhage complicating intravenous thrombolysis: results from the SITS-ISTR. Eur J Neurol. 2023 Oct;30(10):3161-3171. doi: 10.1111/ene.15968. Epub 2023 Jul 14. PMID: 37410547. [PubMed]

107. Aref, Hany & El Nahas, Nevine & Shokri, Hossam & Roushdy, Tamer. (2023). The budget impact of alteplase in the treatment of acute ischemic stroke in Egypt. Frontiers in Neurology. 10.3389/fneur.2023.1220615. [Frontiers]

106. El Nahas N, Aref H, Kenawy FF, Georgy S, Abushady EM, Dawood NL, Hamdy S, Abdelmohsen N, Hassan Abdel Hamid Y, Roushdy T, Shokri H. Stroke in women: experience in a developing country. BMC Neurol. 2023 Jul 17;23(1):271. doi: 10.1186/s12883-023-03314-3. PMID: 37460962; PMCID: PMC10351134. [PubMed]

105. Thorén M, Escudero-Martínez I, Andersson T, Chen SY, Tsao N, Khurana D, Beretta S, Peeters A, Tsivgoulis G, Roffe C, Ahmed N. Reperfusion By Endovascular Thrombectomy And Early Cerebral Edema In Anterior Circulation Stroke: Results From The Sits- International Stroke Thrombectomy Registry. Int J Stroke. 2023 May 24:17474930231180451. doi: 10.1177/17474930231180451. Epub ahead of print. PMID: 37226337. [PubMed]

104. Escudero-Martínez I, Thorén M, Matusevicius M, Cooray C, Zini A, Roffe C, Toni D, Tsivgoulis G, Ringleb P, Wahlgren N, Ahmed N. Association of cholesterol levels with hemorrhagic transformation and cerebral edema after reperfusion therapies. Eur Stroke J. 2023 Mar;8(1):294-300. doi: 10.1177/23969873221148229. Epub 2022 Dec 28. PMID: 37021184; PMCID: PMC10069196. [PubMed]

103. Jalali N, Sadeghi Hokmabadi E, Ghoreishi A, Sariaslan P, Rafie S, Borhani-Haghighi A, Moghadam Ahmadi A, Azin H, Vakilian A, Khalili P, Farhoudi M. Outcome predictors in anterior and posterior ischemic strokes: a study based on the Iranian SITS registry. Sci Rep. 2023 Jan 21;13(1):1231. doi: 10.1038/s41598-023-28465-8. PMID: 36681721; PMCID: PMC9867737. [PubMed]

102. Schwarz G, Cascio Rizzo A, Matusevicius M, Giussani G, Invernizzi P, Melis F, Lesko N, Toni D, Agostoni EC, Ahmed N. Reperfusion Treatments in Disabling Versus Nondisabling Mild Stroke due to Anterior Circulation Vessel Occlusion. Stroke. 2023 Mar;54(3):743-750. doi: 10.1161/STROKEAHA.122.041772. Epub 2023 Feb 27. PMID: 36848431. [AHA Journals]

101. Schwarz G, Bonato S, Lanfranconi S, Matusevicius M, Ghione I, Valcamonica G, Tsivgoulis G, Paiva Nunes A, Mancuso M, Zini A, Candelaresi P, Rand VM, Comi GP, Mazya MV, Ahmed N. Intravenous thrombolysis + endovascular thrombectomy versus thrombolysis alone in large vessel occlusion mild stroke: a propensity score matched analysis. Eur J Neurol. 2023 Feb 6. doi: 10.1111/ene.15722. Epub ahead of print. PMID: 36746650. [PubMed]

100. Escudero-Martínez I, Thorén M, Ringleb P, Nunes AP, Cappellari M, Rand VM, Sobolewski P, Egido J, Toni D, Chen SY, Tsao N, Ahmed N. Cerebral Edema in Patients with severe Hemispheric Syndrome: Incidence, Risk Factors, and Outcomes-Data from SITS-ISTR. J Stroke. 2023 Jan;25(1):101-110. doi: 10.5853/jos.2022.01956. Epub 2022 Dec 6. PMID: 36470246; PMCID: PMC9911855. [Journal of Stroke]

99. Ferreira Cristina S, Fior A, Alves M, Papoila AL, Nunes AP. Functional Outcome of Endovascular Treatment in Patients With Acute Ischemic Stroke With Large Vessel Occlusion: Mothership Versus Drip-and-Ship Model in a Portuguese Urban Region. Cureus. 2022 Dec 18;14(12):e32659. doi: 10.7759/cureus.32659. PMID: 36660499; PMCID: PMC9844243. [PubMed]

98. Tsivgoulis G, Katsanos AH, Christogiannis C, Faouzi B, Mavridis D, Dixit AK, Palaiodimou L, Khurana D, Petruzzellis M, Psychogios K, Macleod MJ, Ahmed N. Intravenous Thrombolysis with Tenecteplase for the Treatment of Acute Ischemic Stroke. Ann Neurol. 2022 Sep;92(3):349-357. doi: 10.1002/ana.26445. Epub 2022 Jul 7. PMID: 35713213. [PubMed]

97. Escudero-Martínez I, Matusevicius M, Pavia-Nunes A, Sevcik P, Nevsimalova M, Rand VM, Kõrv J, Cappellari M, Mikulik R, Toni D, Ahmed N. Association of statin pre-treatment with baseline stroke severity and outcome in patients with acute ischemic stroke and received reperfusion treatment: An observational study. Int J Stroke. 2022 May 11;17474930221095965. doi: 10.1177/17474930221095965. Online ahead of print. PMID: 35403505.

96. Sadeghi-Hokmabadi E, Ghoreishi A, Rikhtegar R, Sariaslani P, Rafie S, Vakilian A, Sharifipour E, Mehrpour M, Saadatnia M, Mirza-Aghazadeh-Attari M, Farhoudi M. Low-dose versus standard-dose alteplase for intravenous thrombolysis in patients with acute ischemic stroke in Iran: Results from the safe implementation of treatments in stroke registry. Curr J Neurol. 2021 Oct 7. doi: http://dx.doi.org/10.18502/cjn.v20i4.8346. [Current Journal of Neurology]

95. Janssen PM, van Overhagen K, Vinklárek J, Roozenbeek B, van der Worp HB, Majoie CB, Bar M, Černík D, Herzig R, Jurák L, Ostrý S, Mikulik R, Lingsma HF, Dippel DWJ; MR CLEAN Registry investigators and the SITS TBY Registry investigators from the Czech Republic. Between-Center Variation in Outcome After Endovascular Treatment of Acute Stroke: Analysis of Two Nationwide Registries. Circ Cardiovasc Qual Outcomes. 2022 Mar;15(3):e008180. doi: 10.1161/CIRCOUTCOMES.121.008180. Epub 2022 Jan 31. PMID: 35094522; PMCID: PMC8920023.

94. Feil K, Matusevicius M, Herzberg M, Tiedt S, Küpper C, Wischmann J, Schönecker S, Mengel A, Sartor-Pfeiffer J, Berger K, Dimitriadis K, Liebig T, Dieterich M, Mazya M, Ahmed N, Kellert L. Minor stroke in large vessel occlusion: A matched analysis of patients from the German Stroke Registry-Endovascular Treatment (GSR-ET) and patients from the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR). Eur J Neurol. 2022 Feb 4. doi: 10.1111/ene.15272. Epub ahead of print. PMID: 35122371.

93. Aref H, Zakaria M, Shokri H, Roushdy T, El Basiouny A, El Nahas N. Changing the landscape of stroke in Egypt. Cerebrovasc Dis Extra. 2021 Dec 3. doi: 10.1159/000521271. Online ahead of print. PMID: 34864736. [PubMed]

92. El Nahas NM, Shokri HM, Roushdy TM, Dawood NL, Abushady EM, Georgy SS, Zaki AS, Bedros RV, Aref HM. Door to Needle Count Down: A 3 Years Experience in an Egyptian University Stroke Center. Neurologist. 2021 Nov 30. doi: 10.1097/NRL.0000000000000372. Online ahead of print. PMID: 34855665. [PubMed]

91. Matusevicius M, Cooray C, Rand VM, Nunes AP, Moreira T, Tassi R, Egido JA, Ollikainen JP, Bigliardi G, Holmin S, Ahmed N. Stroke Etiology and Outcomes after Endovascular Thrombectomy: Results from the SITS Registry and a Meta-Analysis. J Stroke. 2021 Sep;23(3):388-400. doi: 10.5853/jos.2021.00850. Epub 2021 Sep 30. PMID: 34649383. [PubMed]

90. Ahmed N, Mazya M, Nunes AP, Moreira T, Ollikainen JP, Escudero-Martinez I, Bigliardi G, Dorado L, Dávalos A, Egido JA, Tassi R, Strbian D, Zini A, Nichelli P, Herzig R, Jurák L, Hurtikova E, Tsivgoulis G, Peeters A, Nevšímalová M, Brozman M, Cavallo R, Lees KR, Mikulik R, Toni D, Holmin S. Safety and Outcomes of Thrombectomy in Ischemic Stroke With vs Without Intravenous Thrombolysis. Neurology. 2021 Jun 4:10.1212/WNL.0000000000012327. doi: 10.1212/WNL.0000000000012327. Epub ahead of print. PMID: 34088873. [PubMed]

89. Ahmed N, Mazya M, Nunes AP, Moreira T, Ollikainen JP, Escudero-Martinez I, Bigliardi G, Dorado L, Dávalos A, Egido JA, Tassi R, Strbian D, Zini A, Nichelli P, Herzig R, Jurák L, Hurtikova E, Tsivgoulis G, Peeters A, Nevšímalová M, Brozman M, Cavallo R, Lees KR, Mikulik R, Toni D, Holmin S. Safety and outcomes of routine endovascular thrombectomy in large artery occlusion recorded in the SITS Register: An observational study. J Intern Med. 2021 May 17. doi: 10.1111/joim.13302. Epub ahead of print. PMID: 33999451. [PubMed]

88. Anadani M, Matusevicius M, Tsivgoulis G, Peeters A, Nunes AP, Mancuso M, Roffe C, de Havenon A, Ahmed N. Magnitude of blood pressure change and clinical outcomes after thrombectomy in stroke caused by large artery occlusion. Eur J Neurol. 2021 Jun;28(6):1922-1930. doi: 10.1111/ene.14807. Epub 2021 Mar 19. PMID: 33682232. [PubMed]

87. Ahmed N, Lees KR, von Kummer R, Holmin S, Escudero-Martinez I, Bottai M, Jansen O, Wahlgren N; Collaborators. The SITS Open Study: A Prospective, Open Label Blinded Evaluation Study of Thrombectomy in Clinical Practice. Stroke. 2021 Mar;52(3):792-801. doi: 10.1161/STROKEAHA.120.031031. Epub 2021 Feb 10. PMID: 33563015. [PubMed]

86. Tsivgoulis G, Katsanos AH, Ahmed N.Ann Neurol. Reply to “Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke”. 2020 Oct;88(4):859-860. doi: 10.1002/ana.25851. Epub 2020 Aug 5. PMID: 32683728 [PubMed]

85. Cooray C, Karlinski M, Kobayashi A, Ringleb P, Kõrv J, Macleod MJ, Dixit A, Azevedo E, Bladin C, Ahmed N. Safety and early outcomes after intravenous thrombolysis in acute ischemic stroke patients with prestroke disability. Int J Stroke. 2020 Sep 2:1747493020954605. doi: 10.1177/1747493020954605. Online ahead of print. PMID: 32878588 [PubMed]

84. Hossam M. Shokri, Nevine M. El Nahas, Hany M. Aref, Noha L. Dawood, Eman M. Abushady, Eman H. Abd Eldayem, Shady S. Georgy, Amr S. Zaki, Rady Y. Bedros, Mona M. Wahid El Din, Tamer M. Roushdy. Factors related to time of stroke onset versus time of hospital arrival: A SITS registry-based study in an Egyptian stroke center. Plos One 2020 Sep 11;15(9):e0238305. doi: 10.1371/journal.pone.0238305. eCollection 2020 [PubMed]

83. Yu WM, Abdul-Rahim AH, Cameron AC, Körv J, Sevcik P, Toni D, Lees KR and SITS Scientific Committee. The Incidence and Associated Factors of Early Neurological Deterioration After Thrombolysis, Results From SITS Registry. Stroke. 2020 Aug 19:STROKEAHA119028287. doi: 10.1161/STROKEAHA.119.028287 AHA Journals

82. Escudero-Martinez I, Mazya M, Teutsch C, et al. Dabigatran initiation in patients with non-valvular AF and first acute ischaemic stroke: a retrospective observational study from the SITS registryBMJ Open. 2020;10(5):e037234. Published 2020 May 19. doi:10.1136/bmjopen-2020-037234 [BMJ Journals] 

81. Keselman B, Gdovinová Z, Jatuzis D, Melo TPE, Vilionskis A, Cavallo R, Frol S, Jurak L, Koyuncu B, Nunes AP, Petrone A, Lees KR, Mazya MV, Safety and Outcomes of Intravenous Thrombolysis in Posterior Versus Anterior Circulation Stroke: Results From the Safe Implementation of Treatments in Stroke Registry and Meta-Analysis. Stroke. 2020 Mar;51(3):876-882. doi:10.1161/STROKEAHA.119.027071. Epub 2020 Jan 9 [PubMed] 

80. Alhazzani A, Al-Rukn S, Khan M, Moreira T, Wahlgren N. Changing the face of stroke care in the Middle East North Africa region. Stroke. 2020 February 07, Journal of the Neurological Science doi:10.1016/j.jns.2020.116727. [PubMed]

79. Thorén M, Dixit A, Escudero-Martinez I, Gdovinová Z, Klecka L, Rand VM, Toni D, Vilionskis A, Wahlgren N, Ahmed N. Effect of Recanalization on Cerebral Edema in Ischemic Stroke Treated With Thrombolysis and/or Endovascular Therapy. Stroke. 2020 Jan;51(1):216-223. doi: 10.1161/STROKEAHA.119.026692 [PubMed]

78. Matusevicius M,Cooray C, Bottai M, Mazya M, Tsivgoulis G, Nunes AP, Moreira T, Ollikainen J, Tassi R, Strbian D, Toni D, Holmin S, Ahmed N. Blood Pressure After Endovascular Thrombectomy: Modeling for Outcomes Based on Recanalization Status. Stroke. 2019 Dec 11:STROKEAHA119026914. doi:10.1161/STROKEAHA.119.026914. [Epub ahead of print] [PubMed]

77. Al-Rukn S, Mazya M, Akhtar N, Hashim H, Mansouri B, Faouzi B, Aref H, Abdulrahman H, Kesraoui S, Hentati F, Gebelly S, Ahmed N, Wahlgren N, Abd-Allah F, Almekhlafi M, Moreira T. Stroke in the Middle-East and North Africa: A 2-year prospective observational study of intravenous thrombolysis treatment in the region. Results from the SITS-MENA Registry. Int J Stroke. 2019 Oct 8:1747493019874729. doi: 10.1177/1747493019874729. [Epub ahead of print] [PubMed] 

76. Charith Cooray, Michael Mazya,Robert Mikulik, Jurak Lubomir, Miroslav Brozman, Peter Ringleb, Anand Dixit, Danilo Toni, Niaz Ahmed. Safety and outcome of intravenous thrombolysis in acute ischaemic stroke patients on prophylactic doses of low-molecular-weight heparins at stroke onset. Stroke 2019 May;50(5):1149-1155. doi: 10.1161/STROKEAHA.118.024575.[PubMed]

75. Alonso de Leciñana M, Mazya MV, Kostulas N, Del Brutto OH, Abanto C, Massaro AR, de Bastos M, Martins S, Ameriso SF, Gongora-Rivera F, Sacks C, Hoppe A, Abad P, Meza G, Arauz-Gongora A, Wahlgren N, Díez-Tejedor E; SITS-SIECV Investigators. Stroke Care and Application of Thrombolysis in Ibero-America: Report From the SITS-SIECV Ibero-American Stroke Register. Stroke. 2019 Sep;50(9):2507–2512. doi: 10.1161/STROKEAHA.119.025668. Epub 2019 Aug 6. [PubMed]

74. Keselman B, Cooray C, Vanhooren G, Bassi P, Consoli D, Nichelli P, Peeters A, Sanak D, Zini A, Wahlgren N, Ahmed N, Mazya MV. IV thrombolysis in stroke mimics – Results from the SITS International Stroke Thrombolysis Register (SITS-ISTR).  European Journal of Neurology 2019 Aug;26(8):1091-1097. doi: 10.1111/ene.13944. Epub 2019 Mar 25. [PubMed]

73. Marius Matusevicius, Maurizio Paciaroni, Valeria Caso, Matteo Bottai, Dheeraj Khurana, Mario de Bastos, Sheila Cristina Ouriques Martins, Yakup Krespi, Charith Cooray, Danilo Toni, Niaz Ahmed. Outcome after intravenous thrombolysis in patients with acute lacunar stroke, an observational study based on SITS international registry. Int J Stroke. 2019 Apr 1:1747493019840947. doi: 10.1177/1747493019840947. [Epub ahead of print] [PubMed]

72. Al-Rukn S, Mazya MV, Akhtar N, Hashim H, Mansouri B, Faouzi B, Aref H, Abdulrahman H, Kesraoui S, Hentati F, Gebelly S, Ahmed N, Wahlgren N, Abd-Allah F, Almekhlafi M, Moreira T. Stroke in the Middle-East and North Africa: A 2-year prospective observational study of stroke characteristics in the region. Results from the SITS-MENA Registry. Int J Stroke. 2019 Mar 12:1747493019830331. doi: 10.1177/1747493019830331. [Epub ahead of print] [PubMed]

71. Cooray C, Mazya MV, Bottai M, Scheitz JF, Abdul-Rahim AH, Moreira TP, Mikulik R, Krajina A, Nevsimalova M, Toni D, Wahlgren N, Ahmed N. Are you suffering from a large arterial occlusion? Please raise your arm!Stroke Vasc Neurol. 2018 Sep 3;3(4):215-221. doi: 10.1136/svn-2018-000165. eCollection 2018 Dec. PubMed PMID: 30637127; PubMed Central PMCID: PMC6312073. [PMC]

70. Tsivgoulis G, Katsanos AH, Mavridis D, Gdovinova Z, Karliński M, Macleod MJ,StrbianD, Ahmed N. Intravenous Thrombolysis for Ischemic Stroke Patients on Dual Antiplatelets. Ann Neurol. 2018 Jul;84(1):89-97. doi: 10.1002/ana.25269. Epub 2018 Jul 30. PubMed PMID: 30048012. [PubMed]

69. Tsivgoulis G, Geisler F, Katsanos AH, Kõrv J, Kunz A, Mikulik R, Rozanski M, Wendt M, Audebert HJ. Ultraearly Intravenous Thrombolysis for Acute Ischemic Stroke in Mobile Stroke Unit and Hospital Settings: A Comparative Analysis.Stroke. 2018 Jul 9. pii: STROKEAHA.118.021536. doi:10.1161/STROKEAHA.118.021536. [Epub ahead of print] PubMed PMID: 29986934. [PubMed]

68. Tsivgoulis G, Kargiotis O, Rudolf J, Komnos A, Tavernarakis A, Karapanayiotides T, Ellul J, Katsanos AH, Giannopoulos S, Gryllia M, Safouris A, Papamichalis P, Vadikolias K, Mitsias P, Hadjigeorgiou G. Intravenous thrombolysis for acute ischemic stroke in Greece: the Safe Implementation of Thrombolysis in Stroke registry 15-year experience.Ther Adv Neurol Disord. 2018 Jun 28;11:1756286418783578. doi: 10.1177/1756286418783578. eCollection 2018. PubMed PMID: 30034535; PubMed Central PMCID: PMC604860. [PubMed]

67. Mazya MV, Ahmed N, Azevedo E, Davalos A, Dorado L, Karlinski M, Lorenzano S, Neumann J, Toni D, Moreira TP; SITS Investigators. Impact of Transcranial Doppler Ultrasound on Logistics and Outcomes in Stroke Thrombolysis: Results From the SITS-ISTR. Stroke. 2018 Jul;49(7):1695-1700. doi: 10.1161/STROKEAHA.118.021485. Epub 2018 May 29. PMID: 29844031[PubMed]

66. Vaclavik D, Vilionskis A, Jatuzis D, Karlinski MA, Gdovinova Z, Kõrv J, Tsivgoulis G, Mikulik R. Clinical outcome of cardioembolic stroke treated by intravenous thrombolysis. Acta Neurol Scand. 2018 Mar;137(3):347-355. doi: 10.1111/ane.12880. Epub 2017 Dec 8.PMID: 29218699[PubMed]

65. Cappellari M, Turcato G, Forlivesi S, Zivelonghi C, Bovi P, Bonetti B, Toni D. TARTING-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis for Stroke.Stroke. 2018 Feb;49(2):397-404. doi:10.1161/STROKEAHA.117.018427. Epub 2018 Jan 8. PMID: 29311264 [PubMed]

64. Mundiyanapurath S, Hees K, Ahmed N, Wahlgren N, Uhlmann L, Kieser M, Ringleb PA, Hacke W, Nagel S. Predictors of symptomatic intracranial haemorrhage in off-label thrombolysis: an analysis of the Safe Implementation of Treatments in Stroke registry.Eur J Neurol. 2018 Feb;25(2):340-e11. doi: 10.1111/ene.13507. Epub 2017 Dec 2. PMID: 29105904 [PubMed]

63. Volny O, Krajina A, Belaskova S, Bar M, Cimflova P, Herzig R, Sanak D, Tomek A, Köcher M, Rocek M, Padr R, Cihlar F, Nevsimalova M, Jurak L, Havlicek R, Kovar M, Sevcik P, Rohan V, Fiksa J, Menon BK, Mikulik R. Mechanical thrombectomy performs similarly in real worldpractice: a 2016 nationwide study from the Czech Republic. J Neurointerv Surg. 2018 Aug;10(8):741-745. doi:10.1136/neurintsurg-2017-013534. Epub 2017 Nov 16. PubMed PMID: 29146830. [PubMed]

62. Ahmed N, Lees KR, Ringleb PA, Bladin C, Collas D, Toni D, Ford GA; The SITS Investigators. Outcome after stroke thrombolysis in patients >80 years treated within 3 hours vs >3-4.5 hours.Neurology. 2017 Oct 10;89(15):1561-1568. doi: 10.1212/WNL.0000000000004499. Epub 2017 Sep 8. PMID: 28887377 [PubMed]

61. Thorén M, Azevedo E, Dawson J, Egido JA, Falcou A, Ford GA, Holmin S, Mikulik R, Ollikainen J, Wahlgren N, Ahmed N. Predictors for Cerebral Edema in Acute Ischemic Stroke Treated With Intravenous Thrombolysis.Stroke. 2017 Sep;48(9):2464-2471. doi: 10.1161/STROKEAHA.117.018223. Epub 2017 Aug 3. PMID: 28775140 [PubMed]

60. Kellert L, Hametner C, Ahmed N, Rauch G, MacLeod MJ, Perini F, Lees KR, Ringleb PA; SITS Investigators. Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis.Stroke. 2017 Jul;48(7):1827-1834. doi: 10.1161/STROKEAHA.117.016876. Epub 2017 May 25. PMID: 28546325 [PubMed] 

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44. Novotná J, Kadlecová P, Czlonkowska A, Brozman M, Švigelj V, Csiba L, Kõrv J, Demarin V, Vilionskis A, Mikulík R; SITS-EAST Investigators. Hyperdense cerebral artery computed tomography sign is associated with stroke severity rather than stroke subtype. J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):2533-9. doi: 10.1016/j.jstrokecerebrovasdis.2014.04.034. Epub 2014 Sep 27. PubMed PMID: 25267589. [PubMed]

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36. Kharitonova TV, Melo TP, Andersen G, Egido JA, Castillo J, Wahlgren N; SITS investigators. Importance of cerebral artery recanalization in patients with stroke with and without neurological improvement after intravenous thrombolysis. Stroke. 2013 Sep;44(9):2513-8. doi: 10.1161/STROKEAHA.111.000048. Epub 2013 Jul 23. PubMed PMID: 23881960. [PubMed]

35. Mazya MV, Lees KR, Markus R, Roine RO, Seet RC, Wahlgren N, Ahmed N; for the SITS investigators. Safety of IV thrombolysis for ischemic stroke in patients treated with warfarin. Ann Neurol. 2013 Jun 6. doi: 10.1002/ana.23924. [Epub ahead of print]. PubMed PMID: 23744571. [PubMed]

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33. Mazya MV, Bovi P, Castillo J, Jatuzis D, Kobayashi A, Wahlgren N, Ahmed N. External Validation of the SEDAN Score for Prediction of Intracerebral Hemorrhage in Stroke Thrombolysis. Stroke. 2013 Jun;44(6):1595-600. doi: 10.1161/STROKEAHA.113.000794. Epub 2013 Apr 30. PubMed PMID: 23632975. [PubMed]

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31. Rha JH, Shrivastava VP, Wang Y, Lee KE, Ahmed N, Bluhmki E, Hermansson K, Wahlgren N, for the SITS investigators. Thrombolysis for acute ischemic stroke with alteplase in an Asian population: results of the multicenter, multinational, Safe Implementation of Thrombolysis in Stroke-Non European Union World (SITS-NEW). In J Stroke 2012, Epub 2012 Sep 18. PubMed PMID:25588617.[PubMed]

30. Strbian D, Ahmed N, Wahlgren N, Kaste M, Tatlisumak T, for SITS investigators. Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia: analysis of Safe Implementation of Thrombolysis in Stroke – International Stroke Thrombolysis Register (SITS-ISTR). Stroek 2012; 43: 2695-2698, Epub 2012 Jul 17. PubMed PMID:22811459. [PubMed]   

29. Mazya M, Egido J, Ford G, Lees K, Mikulik R, Toni D, Wahlgren N, Ahmed N; For the SITS investigators. Predicting the Risk of Symptomatic Intracerebral Hemorrhage in Ischemic Stroke Treated With Intravenous Alteplase: Safe Implementation of Treatments in Stroke (SITS) Symptomatic Intracerebral Hemorrhage Risk Score. Stroke 2012; 43:1524-1531, Epub 2012 March 22. PubMed PMID:22442178. [PubMed] 

28. Mikulík R, Kadlecová P, Czlonkowska A, Kobayashi A, Brozman M, Svigelj V, Csiba L, Fekete K, Kõrv J, Demarin V, Vilionskis A, Jatuzis D, Krespi Y, Ahmed N; for the Safe Implementation of Treatments in Stroke-East Registry (SITS-EAST) Investigators. Factors Influencing In-Hospital Delay in Treatment With Intravenous Thrombolysis. Stroke. 2012 Mar 15. [Epub ahead of print]

27. Karlinski M, Kobayashi A, Mikulik R, Sanak D, Wahlgren N, Czlonkowska A. Intravenous alteplase in ischemic stroke patients not fully adhering to the current drug license in Central and Eastern Europe. Int J Stroke. 2012 Feb 7. doi: 10.1111/j.1747-4949.2011.00733.x. [Epub ahead of print]

26. Toni D, Ahmed N, Anzini A, Lorenzano S, Brozman M, Kaste M, Mikulik R, Putaala J, Wahlgren N; For the SITS investigators. Intravenous thrombolysis in young stroke patients: Results from the SITS-ISTR. Neurology. 2012 Mar 7. [Epub ahead of print]

25. Mishra NK, Ahmed N, Davalos A, Iversen HK, Melo T, Soinne L, Wahlgren N, Lees KR; SITS and VISTA collaborators. Thrombolysis outcomes in acute ischemic stroke patients with prior stroke and diabetes mellitus. Neurology. 2011 Nov 22;77(21):1866-72. Epub 2011 Nov 16. PubMed PMID: 22094479. [PubMed – indexed for MEDLINE]

24. Zinkstok SM, Vergouwen MD, Engelter ST, Lyrer PA, Bonati LH, Arnold M, Mattle HP, Fischer U, Sarikaya H, Baumgartner RW, Georgiadis D, Odier C, Michel P, Putaala J, Griebe M, Wahlgren N, Ahmed N, van Geloven N, de Haan RJ, Nederkoorn PJ. Safety and functional outcome of thrombolysis in dissection-related ischemic stroke: a meta-analysis of individual patient data. Stroke. 2011 Sep;42(9):2515-20. Epub 2011 Jul 28. Review. [PubMed]

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22. Diedler J, Ahmed N, Glahn J, Grond M, Lorenzano S, Brozman M, Sykora M, Ringleb P. Is the Maximum Dose of 90 mg Alterplase Sufficient for Patients With Ischemic Stroke Weighing > 100 kg? Stroke. 2011 Jun;42(6):1615-20. Epub 2011 Apr 14. [PubMed]

21. Topakian R, Brainin M, Eckhardt R, Kiechl S, Ahmed N, Ferrari J, Iglseder B, Wahlgren NG, Lang W, Fazekas F, Willeit J, Aichner FT; for the SITS-Austria group. Thrombolytic therapy for acute stroke in Austria: data from the Safe Implementation of Thrombolysis in Stroke (SITS) register. Eur J Neurol. 2011 Feb;18(2):306-11. [PubMed]

20. Mishra, NK, Ahmed N, Andersen G, Egido J, Lindsberg P, Ringleb PA, Wahlgren N, Lees KR for the VISTA and SITS collaborators. Thrombolysis in the very elderly: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. BMJ. 2010 Nov 23;341:c6046. [PubMed]

19. Ford GA, Ahmed N, Azevedo E, Grond M, Larrue V, Lindsberg P, Toni D, Wahlgren N. Intravenous alteplase for stroke in those older than 80 years old. Stroke. 2010 Nov;41(11):2568-74. Epub 2010 Oct 7. [PubMed]

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17. Ahmed N, Dávalos A, Eriksson N, Ford GA, Glahn J, Hennerici M, Mikulik R, Kaste M, Lees KR, Lindsberg P, Toni D, for the SITS Investigators. Association of admission blood glucose and outcome in patients treated with intravenous thrmbolysis. Arch Neurol 201; 67(9): 1123-1130. [PubMed]

16. Diedler J, Ahmed N, Sykora M, Uyttenboogaart M, Overgaard K, Luijckx G-J, Soinne L, Ford GA, Lees KR, Wahlgren N, Ringleb P. Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset. Stroke. 2010 Feb;41(2):288-94. Epub 2010 Jan 7. [PubMed]

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14. Vanacker P, Thijs V, Peeters A, BruneelB, Laloux P, Druwé P, De DeynP, Ahmed N, Wahlgren N, Vanhooren G; Belgian SITS-collaboration group. The Belgian experience with intravenous thrombolysis for acute ischemic stroke. Acta Neurol Belg. 2010 Jun;110(2):157-62. [PubMed]

13. Wahlgren N. Systemic thrombolysis in clincal practice: what have we learned after the Safe Implementation of Thrombolysis in Stroke Monitoring Study? Cerebrovasc Dis. 2009;27 Suppl 1:168-76. Epub 2009 Apr 3. Review. [PubMed]

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11. Mikulík R, Václavík D, Sanák D, Bar M, Sevcík P, Kalita Z, Wahlgren N. A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic. J Neurol. 2010 Jan;257(1):31-7. Epub 2009 Jul 23. [PubMed]***

10. Kharitonova T, Thorén M, Ahmed N, Wardlaw JM, von Kummer R, Thomassen L, Wahlgren N, for the SITS investigators. Disappearing Hyperdense Middle Cerebral Artery Sign in ischemic stroke patients treated. J Neurol Neurosurg Psychiatry. 2009 Mar;80(3):248. Epub 2008 Oct 17. [PubMed]

09. Kobayashi A, Czlonkowska A, Ahmed N, Romanowicz S, Glonek M, Nyka WM, Opala G, Wahlgren N; for the SITS Poland Collaborative Group. Intravenous recombinant tissue plasminogen activator for acute stroke in Poland: an analysis based on the Safe Implementation of Thrombolysis in Stroke (SITS) Registry. Acta Neurol Scand. 2010 Oct;122(4):229-36. [PubMed]

08. Roje-Bedeković M, Vargek-Solter V, Corić L, Sabolek K, Breitenfeld T, Supanc V, Demarin V. Thrombolysis for acute ischemic stroke–our experiences as part of SITS-MOST. Acta Clin Croat. 2009 Sep;48(3):287-93.** [PubMed]

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06. Rodríguez-Yáñez M, Alvarez-Sabín J, Dávalos A, Díez-Tejedor E, Castillo J. Thrombolytic therapy for acute ischemic stroke. Experience of SITS (Safe Implementation of Thrombolysis in Stroke) register. Neurologia. 2009 Jun;24(5):288-91. Spanish.* [PubMed]

05. Lorenzano S, Ahmed N, Rosselli A, Marcello N, Inzitari D, Sterzi R, Wahlgren N, Prencipe M, Toni D. Safe implementation of thrombolysis in stroke-monitoring study in Italy. Eur J Neurol. 2010 Jan;17(1):163-7.Jun 15. [Epub ahead of print June 2009]. [PubMed]

04. Wahlgren N, Ahmed N, Dávalos A, Hacke W, Millán M, Muir K, Roine RO, Toni D, Lees KR. Thrombolysis with alteplase 3-4.5 h after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 2008; 372: 1303-1309. [PubMed]

03. Lees KR, Ford GA, Muir KW, Ahmed N, Dyker AG, Atula S, Kalra L, Warburton EA, Baron JC, Jenkinson DF, Wahlgren NG, Walters MR; SITS-UK Group. Thrombolytic therapy for acute stroke in the United Kingdom: experience from the safe implementation of thrombolysis in stroke (SITS) register. QJM. 2008 Nov;101(11):863-9. Epub 2008 Aug 11. [PubMed]

02. Wahlgren N, Ahmed A, Eriksson N, Aichner F, Bluhmki E, Dávalos A, Erilä T, Ford GA, Grond M, Hacke W, Hennerici M, Kaste M, Köhrmann M, Larrue V, Lees KR, Machnig T, Roine RO, Toni D, Vanhooren G, for the SITS-MOST investigators. Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials; Safe Implementation of Thrombolysis in Stroke Monitoring Study (SITS-MOST). Stroke 2008; 39: 3316-3322. [PubMed]

01. Wahlgren N, Ahmed N, Davalos A, Ford GA, Grond M, Hacke W, Hennerici MG, Kaste M, Külkens S, Larrue V, Lees KR, Roine RO, Soinne L, Toni D, Vanhooren G: Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 2007;369:275-282. [PubMed]

* Published independently by the Spanish group.

** Published independently by the Croatian group.

*** This paper is including data from SITS but also data collected for a wider group of patients than iv thrombolysis.